Tight Glycemic Control in the Hospital

Tight glycemic control in critically ill adults.

Tight Glycemic Control in Critically Ill Children.

BACKGROUND In multicenter studies, tight glycemic control targeting a normal blood glucose level has not been shown to improve outcomes in critically ill adults or children after cardiac surgery. Studies involving critically ill children who have not undergone cardiac surgery are lacking. METHODS In a 35-center trial, we randomly assigned critically ill children with confirmed hyperglycemia (...

Sliding scale versus tight glycemic control in the noncritically ill at a community hospital.

BACKGROUND Development of hyperglycemia during hospitalization is an area of concern in patients with and without diabetes mellitus. Tight glycemic control has been debated for critically ill and noncritically ill patients with hyperglycemia. Although many studies have been performed in the critically ill, adequate data are not available in the noncritically ill population. OBJECTIVE To compa...

Tight glycemic control in the ICU - is the earth flat?

Tight glycemic control in the ICU has been shown to reduce mortality in some but not all prospective randomized control trials. Confounding the interpretation of these studies are differences in how the control was achieved and underlying incidence of hypoglycemia, which can be expected to be affected by the introduction of continuous glucose monitoring (CGM). In this issue of Critical Care, a ...

Evidence-lost to tight glycemic control?

In recent years, the field of intensive care medicine has had the benefit of learning from two randomized controlled trials that tight glycemic control (TGC) is beneficial to critically ill patients [1,2]. No benefit was found by two other clinical trials, however, hampering implementation of TGC in daily practice [3,4]. The question arises of whether the intensive care community interprets the...